تحضير ودراسة الفعالية المضادة للبكتريا لبعض مركبات التترازول الثنائية الجديدة المشتقة من 4,4-أزو ثنائي بنزالديهايد

تحضير ودراسة الفعالية المضادة للبكتريا لبعض مركبات التترازول الثنائية الجديدة المشتقة من 4,4-أزو ثنائي بنزالديهايد

هديه سالم عبد

فوزي حميد جمعة

قسم الكيمياء / كلية التربية للبنات / جامعة تكريت

Abstract

In this study new Schiff bases compounds had been prepared including reaction of (4,4-Azo dibenzaldehyde) methanone with substituted aniline [H1-H5]. Schiff bases were converted into tetrazolederivatives [H6-H10] by the reaction of Schiff bases with sodium azideinabsolutein ethanol .The prepared compounds were characterized by color and melting point,UV-Vis, FT-IR, spectral analysis. Some of the prepared compounds were identified by 1H-NMR spectra. The liquid crystalline properties of some prepared compounds were also studied and the antibacterial activities were studied against different kinds of bacteria namely Pseudomonas  aeruginosa Gram(-ve) and Staphylococcus aureus Gram(+ve).

Key words : Schiff bases of 4,4-azodibenzaldehyde,Tetrazole