توصيف وانتشار عزلات كليبسلا الرئوية من تجويف الفم

توصيف وانتشار عزلات كليبسلا الرئوية من تجويف الفم

آية محمود محمد
مروة حسن عبد الوهاب
قسم الأحياء الدقيقة / كلية العلوم / جامعة تكريت / تكريت / العراق

ABSTRACT
Klebsiella is a significant human pathogen that causes opportunistic infections in healthcare settings and the general population. An escalating public health problem related to Klebsiella Pneumoniae is the rising prevalence of strains resistant to multiple drugs.
The present investigation involved the collection of 150 oral cavity swab samples from a diverse group of individuals of varying genders and ages, randomly selected from ENT patient in azadi hospital. All 150 (100%) samples exhibited positive bacterial growth in the cultures, with none showing negative results. No bacterial growth was seen in 0% of the samples. The isolates were identified using biochemical assays and the Vitek2 system.
The study revealed that Klebsiella Pneumoniae is a prevalent pathogen in the oral microbiome, especially in individuals with chronic conditions. The bacteria are encapsulated, Gram-negative rods with distinct biochemical profiles. There is a potential connection between Klebsiella Pneumoniae and diabetes and hypertension, indicating a higher vulnerability to infections. However, asthma and thyroid disorders have a weaker association. These findings emphasize the importance of monitoring and using targeted antibiotic treatments for Klebsiella Pneumoniae infections, particularly in chronically ill patients.
Klebsiella Pneumoniae, a prevalent oral pathogen in the sampled population, is linked to chronic illnesses like hypertension and diabetes, highlighting the need for understanding and managing these infections, particularly in individuals with chronic health conditions, for effective infection prevention and therapy.
Keywords: Klebsiella Pneumonia, MDR, Antibiotic Resistance.